pot-1 Antibody

Code CSB-PA331388XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pot-1 Polyclonal antibody
Uniprot No.
Target Names
pot-1
Alternative Names
pot-1 antibody; CeOB2 antibody; B0280.10 antibody; Protection of telomeres homolog 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pot-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Telomeric DNA-binding protein, which binds to single-stranded C-rich repeat sequences, with high specificity to the 5'-GCCTAA-3' sequence. Repeat sequence binding can be at the 5' or 3' telomeric end. May have a role in protecting the 5' end of the C-rich strand of the telomere. Acts redundantly with pot-2 to negatively regulate telomerase-mediated telomere extension. Also regulates telomere length by the telomerase-independent telomere maintenance pathway called ALT (alternative lengthening of telomeres). Through sun-1, anchors telomeres to the nuclear envelope in embryos.
Subcellular Location
Nucleus. Nucleus envelope. Chromosome, telomere.
Tissue Specificity
Expressed in sperm and oocytes.
Database Links

KEGG: cel:CELE_B0280.10

STRING: 6239.B0280.10

UniGene: Cel.10966

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