PP2A2 Antibody

Code CSB-PA574401XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PP2A2 Polyclonal antibody
Uniprot No.
Target Names
PP2A2
Alternative Names
PP2A2 antibody; PP2A1 antibody; At1g10430 antibody; T10O24.4 antibody; Serine/threonine-protein phosphatase PP2A-2 catalytic subunit antibody; EC 3.1.3.16 antibody; Protein phosphatase 2A isoform 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PP2A2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Dephosphorylates and activates the actin-depolymerizing factor ADF1, which, in turn, regulates actin cytoskeleton remodeling and is involved in the blue light photoreceptor PHOT2-mediated chloroplast avoidance movements. Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins. Acts as negative regulator of abscisic acid (ABA) signaling. May regulate ABA-dependent gene expression. Involved in the light-dependent activation of nitrate reductase.
Gene References into Functions
  1. PP2A-2 regulated the activation of ADF/cofilin, which, in turn, regulated actin cytoskeleton remodeling and was involved in phot2-mediated chloroplast avoidance movements. PMID: 22642987
  2. Phenotypic, genetic and gene expression data strongly suggest that PP2Ac-2 is a negative regulator of the abscisic acid pathway. PMID: 17617176
Subcellular Location
Cytoplasm, cytosol. Nucleus. Peroxisome.
Protein Families
PPP phosphatase family, PP-2A subfamily
Tissue Specificity
Expressed in root meristem, emerging lateral roots, leaf vasculature, stipules, guard cells, anthers and pollen grains.
Database Links

KEGG: ath:AT1G10430

STRING: 3702.AT1G10430.1

UniGene: At.21842

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