PTC1 Antibody

1. Data show that Ptc1 is required for proper G2-M cell cycle transition after activation of the cell wall integrity pathway. PMID: 27169355
2. biochemical and genetic evidence that Mkk1 transmits most of the signaling through the CWI pathway and that Ptc1 directly downregulates the CWI pathway at the level of the MAPKKs PMID: 26546002
3. Ptc1 has overlapping functions with Reg1-Glc7 and Sit4 in glucose regulation of SNF1/AMPK and cell viability. PMID: 24019512
4. Ptc1p regulates Mmr1p phosphorylation, localization, and function. PMID: 22119524
5. Nbp2 serves as the network hub and brings seven kinases in close contact to Ptc1. PMID: 21118957
6. Expression profiling of the 6 protein phosphatase 2C family and the effects of mutation of the Ptc1 gene on gene expression and phenotype are reported PMID: 16973600
7. These findings indicate that Ptc1p and Nbp2p regulate endoplasmic reticulum inheritance through the cell wall integrity (CWI) mitogen-activated protein kinase (MAPK) pathway by modulating the MAPK, Slt2p. PMID: 16977319
8. PTC1 promotes the association of myosin-V with its organelle-specific adaptor proteins. PMID: 19116310
9. Results show that Ptc1, a type 2C protein phosphatase, is required for the normal functioning of the TOR pathway. PMID: 19273591

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KEGG: sce:YDL006W

STRING: 4932.YDL006W