Ppn Antibody

Code CSB-PA774736XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Ppn Polyclonal antibody
Uniprot No.
Target Names
Ppn
Alternative Names
Ppn antibody; CG33103 antibody; Papilin antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ppn protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Essential extracellular matrix (ECM) protein that influences cell rearrangements. May act by modulating metalloproteinases action during organogenesis. Able to non-competitively inhibit procollagen N-proteinase, an ADAMTS metalloproteinase.
Gene References into Functions
  1. Drosophila, which has a compact genome, expresses three splice variants of papilin during embryogenesis in developmentally defined patterns. PMID: 12666201
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein Families
Papilin family
Tissue Specificity
During embryogenesis it first appears in the extracellular matrix during gastrulation and early mesoderm development at sites where basement membranes do not subsequently form. Later, migrating hemocytes prominently produce it together with other ECM comp
Database Links

KEGG: dme:Dmel_CG33103

STRING: 7227.FBpp0291051

UniGene: Dm.7007

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