PRF2 Antibody

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Code	CSB-PA669239XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PRF2 Polyclonal antibody

Uniprot No.

Q42418

Target Names

PRF2

Alternative Names

PRF2 antibody; PFN2 antibody; PRO2 antibody; At4g29350 antibody; F17A13.170 antibody; Profilin-2 antibody; AtPROF2 antibody; AthPRF2 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana PRF2 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Binds to actin monomers and regulates the organization of the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. At low concentrations, associates with the poly-proline motif of formins to enhance actin filament elongation rate. Binds G-actin and poly-L-proline with low affinity in vitro. Binds ACT1, ACT7 and ACT11 and inhibits actin polymerization. May be involved in the cross-talk between vesicular trafficking and the actin cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. Inhibits cell growth of various pathogenic fungal strains. May play a role as antifungal proteins in the defense system against fungal pathogen attacks.

Gene References into Functions

Upregulation of profilin 2 by BFA was verified by immunoblot and live imaging at subcellular level. PMID: 21090759
localized to polygonal meshes resembling the endoplasmic reticulum PMID: 19200149

Subcellular Location

Cytoplasm, cytoskeleton. Endoplasmic reticulum. Cytoplasm, cytosol. Nucleus.

Protein Families

Profilin family

Tissue Specificity

Expressed in vascular bundles of roots, hypocotyls, cotyledons, leaves, sepals, petals, stamen filaments and stalks of developing seeds. Expressed in leaf epidermal cells, trichomes and stem epidermal cells. Detected in phloem exudates (at protein level).

Database Links

KEGG: ath:AT4G29350

STRING: 3702.AT4G29350.1

UniGene: At.24227

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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PRF2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background