PRX1 Antibody

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Code	CSB-PA335907XA01SVG
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Product Details

Full Product Name

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PRX1 Polyclonal antibody

Uniprot No.

P34227

Target Names

PRX1

Alternative Names

PRX1 antibody; YBL064C antibody; YBL0503 antibody; YBL0524 antibody; Peroxiredoxin PRX1 antibody; mitochondrial antibody; Prx antibody; EC 1.11.1.15 antibody; 1-Cys PRX antibody; Mitochondrial thiol peroxidase antibody; mTPx antibody; Thioredoxin peroxidase antibody

Raised in

Rabbit

Species Reactivity

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PRX1 protein

Immunogen Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Involved in mitochondrial protection of cadmium-induced oxidative stress.

Gene References into Functions

Oct1 cleaved eight amino acid residues from the N-terminal region of Prx1 inside the matrix, without interfering with its peroxidase activity in vitro PMID: 28821623
Prx1p is fairly well protected from overoxidation, questioning its role in a floodgate mechanism for H2O2 signaling PMID: 26159064
these findings suggest that Srx1 regulates YPrx1 function and structure in yeast cells through a direct interaction. PMID: 23396059
glucose repression effect is mediated by TOR1 and RAS2 through inhibition of MSN2/4 PMID: 15598536
x ray crystallogaphy, molecular structure, amino acid sequence and sequence homology with other species, including human PMID: 16245326
The yeast mitochondrial 1-Cys Prx1 is reactivated by glutathionylation of the catalytic cysteine residue and subsequent reduction by thioredoxin reductase (Trr2) coupled with glutathione (GSH). PMID: 19332553

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Subcellular Location

Mitochondrion.

Protein Families

Peroxiredoxin family, Prx6 subfamily

Database Links

KEGG: sce:YBL064C

STRING: 4932.YBL064C

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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PRX1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background