pry-1 Antibody

Code CSB-PA524000XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pry-1 Polyclonal antibody
Uniprot No.
Target Names
pry-1
Alternative Names
pry-1 antibody; C37A5.9 antibody; Axin-like protein pry-1 antibody; Protein polyray antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pry-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Works in parallel with axl-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Inhibits Wnt signaling, which affects tissue specific expression of Hox genes, egl-5, lin-39 and mab-5. This in turn affects QR (postembryonic neuroblast) cell migration, vulval cell fate specification, and the development of sensory structures by the seam cell lineage. Has a role in alae V cell patterning, ray formation in the male tail and axon guidance. Does not affect B cell polarity.
Subcellular Location
Cell membrane. Nucleus. Cytoplasm, cell cortex.
Tissue Specificity
Expressed in hypodermal cells (seam cells) V5 and V6, Q neuroblasts, ventral hypodermal cells P7/8 to P11/12, body wall muscle cells and neurons in the head, the tail and the ventral nerve cord.
Database Links

KEGG: cel:CELE_C37A5.9

STRING: 6239.C37A5.9

UniGene: Cel.8800

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