PRY3 Antibody

Code CSB-PA344427XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PRY3 Polyclonal antibody
Uniprot No.
Target Names
PRY3
Alternative Names
PRY3 antibody; YJL078C antibody; J1027 antibody; Cell wall protein PRY3 antibody; Pathogenesis-related protein 3 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PRY3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
The full-length isoform (isoform Long) is a daughter cell-specific cell wall protein required for efficient export of lipids such as acetylated sterols. Acts in detoxification of hydrophobic compounds. Involved in tolerance to organic solvents such as dimethyl sulfoxide (DMSO). Plays also a role as an inhibitor of mating. STE12 is utilized as a repressor of full-length PRY3 transcription, ensuring efficient mating.; There is no evidence that production of the short PRY3 transcript (isoform Short) is anything more than an adventitious by-product of the mechanism responsible for the repression of the full-length transcript. Moreover, no disadvantage is detectable for cells unable to make the short transcript.
Gene References into Functions
  1. Results suggest that Ste12p is utilized as a repressor of full-length PRY3 transcription, ensuring efficient mating. PMID: 16940175
Subcellular Location
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP). The short isoform lacks the predicted signal peptide and might have an alternate localization.
Protein Families
CRISP family
Database Links

KEGG: sce:YJL078C

STRING: 4932.YJL078C

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