pam-1 Antibody

Datasheet

Code	CSB-PA982120XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans pam-1 Polyclonal antibody

Uniprot No.

Q4TT88

Target Names

pam-1

Alternative Names

pam-1 antibody; F49E8.3 antibody; Puromycin-sensitive aminopeptidase antibody; PSA antibody; EC 3.4.11.14 antibody; Cytosol alanyl aminopeptidase antibody; AAP-S antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans pam-1 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Aminopeptidase. Required for the exit from meiosis, probably upstream of cyclin cyb-3. Involved in the establishment of the anterior-posterior polarity at the embryonic 1-cell stage by regulating the dynamics of sperm-donated centrosomes. Plays a role in oocyte maturation. Required for embryonic development.

Gene References into Functions

clusters phylogenetically with the puromycin-sensitive aminopeptidase, despite attenuated sensitivity toward puromycin; functions in embryo development and reproduction of the nematode PMID: 12930831
Data show that the puromycin-sensitive aminopeptidase PAM-1 is required for meiotic exit and anteroposterior polarity in the one-cell Caenorhabditis elegans embryo. PMID: 17021038

Subcellular Location

Cytoplasm. Cytoplasm, cell cortex. Chromosome. Cytoplasm, cytoskeleton, spindle pole.

Protein Families

Peptidase M1 family

Tissue Specificity

Expressed mainly in intestinal cells in the posterior part of the intestine and in amphid sensory neurons and nerve ring neurons. Expressed in neurons in the male tail. Expressed in mature spermatids (at protein level).

Database Links

KEGG: cel:CELE_F49E8.3

STRING: 6239.F49E8.3b

UniGene: Cel.34182

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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