Rpn6 Antibody

Code CSB-PA954775XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Rpn6 Polyclonal antibody
Uniprot No.
Target Names
Rpn6
Alternative Names
Rpn6 antibody; CG10149 antibody; 26S proteasome non-ATPase regulatory subunit 11 antibody; 26S proteasome regulatory complex subunit p42B antibody; 26S proteasome regulatory subunit Rpn6 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Rpn6 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly. May act as linker between 19S regulatory subunit and the 20S proteasome core.
Gene References into Functions
  1. Rpn6 has a pivotal role in stabilizing the otherwise weak interaction between the core particle and the regulatory particle. PMID: 22187461
  2. Analyses of an Rpn6 P element insertion mutant and newly generated Rpn6 alleles reveal that Rpn6 is essential for Drosophila development. PMID: 12426099
Protein Families
Proteasome subunit S9 family
Database Links

KEGG: dme:Dmel_CG10149

STRING: 7227.FBpp0086603

UniGene: Dm.3085

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