RPN10 Antibody

Code CSB-PA018908XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) RPN10 Polyclonal antibody
Uniprot No.
Target Names
RPN10
Alternative Names
RPN10 antibody; MBP1 antibody; MCB1 antibody; At4g38630 antibody; F20M13.190 antibody; T9A14.7 antibody; 26S proteasome non-ATPase regulatory subunit 4 homolog antibody; 26S proteasome regulatory subunit RPN10 antibody; AtRPN10 antibody; 26S proteasome regulatory subunit S5A homolog antibody; Multiubiquitin chain-binding protein 1 antibody; AtMCB1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana RPN10 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a role in maintaining the structural integrity of the 19S regulatory particle (RP), subcomplex of the 26S proteasome. Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a potential docking subunit for both ubiquitin receptors RAD23s and DSK2s. Plays a role in the growth and development via the proteasome-dependent degradation of the ABA-signaling protein ABI5/DPBF1. Plays an important role for balancing cell expansion with cell proliferation rates during shoot development.
Gene References into Functions
  1. Data suggest that RPN10 potentially plays a unique and central role in ubiquitin/proteasome-mediated proteolysis substrate recognition. PMID: 21764993
Protein Families
Proteasome subunit S5A family
Tissue Specificity
Ubiquitous with highest expression in flowers.
Database Links

KEGG: ath:AT4G38630

STRING: 3702.AT4G38630.1

UniGene: At.1553

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