CHO1 Antibody

Code CSB-PA357396XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) CHO1 Polyclonal antibody
Uniprot No.
Target Names
CHO1
Alternative Names
CHO1; PSS; PSS1; YER026C; CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) CHO1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Gene References into Functions
  1. In this study, we found that Cho1p, like mammalian PS synthases is inhibited by its product, PS. This suggests a simple mechanism of activating Cho1p at membrane contact sites (MCSs); PS transport out of the ER at MCSs will stimulate Cho1p activity in these regions. PMID: 28119445
  2. overexpression of CHO1 suppresses defects in the endocytic recycling pathway in flippase mutants. These results suggest that flippase-dependent vesicle formation is mediated by phospholipid flipping. PMID: 24390140
  3. Respiratory deficiency mediates the regulation of CHO1 by mRNA stability in Saccharomyces cerevisiae. PMID: 17761681
Subcellular Location
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein.
Protein Families
CDP-alcohol phosphatidyltransferase class-I family
Database Links

KEGG: sce:YER026C

STRING: 4932.YER026C

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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