PTEN2A Antibody

Code CSB-PA189695XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) PTEN2A Polyclonal antibody
Uniprot No.
Target Names
PTEN2A
Alternative Names
PTEN2A antibody; PTEN2 antibody; At3g19420 antibody; MLD14.15 antibody; Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN2A antibody; EC 3.1.3.48 antibody; EC 3.1.3.67 antibody; Protein PHOSPHATASE AND TENSIN HOMOLOG 2-a antibody; AtPTEN2 antibody; AtPTEN2a antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana PTEN2A protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Binds phosphatidic acid. Protein tyrosine phosphatase that exhibits also lipid phosphatase activity. Hydrolyzed poorly p-nitrophenyl phosphate (p-NPP). Can use PtdIns isomers as substrates. Removes efficiently phosphate from the D3 position of the inositol ring, less from the D4 position and not at all from the D5 position on monophosphorylated PtdIns isomers (PIPs). The presence of a phosphate group in the D5 position on PIP(2) isomers reduces lipid phosphatase activity. Mostly active on PtdIns(3)P and PtdIns(3,4)P(2), to a lower extent, on PtdIns(4)P and PtdIns(3,5)P(2), but barely against PtdIns(3,4,5)P(3) as substrate.
Gene References into Functions
  1. PTEN2 comprises of AtPTEN2a and AtPTEN2b proteins in Arabidopsis. AtPTEN2a and AtPTEN2b are differentially regulated in response to salinity and osmotic stress. Moreover, AtPTEN2a effectively binds the signalling lipid phosphatidic acid. [PTEN2a] PMID: 21864294
Protein Families
PTEN phosphatase protein family
Tissue Specificity
Expressed in seedlings, roots, stems, leaves, flowers and siliques. However, at protein level, not observed in older leaves and mature siliques.
Database Links

KEGG: ath:AT3G19420

STRING: 3702.AT3G19420.1

UniGene: At.5710

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