PTR2 Antibody

Code CSB-PA333748XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PTR2 Polyclonal antibody
Uniprot No.
Target Names
PTR2
Alternative Names
PTR2 antibody; YKR093W antibody; YKR413 antibody; Peptide transporter PTR2 antibody; Peptide permease PTR2 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PTR2 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Uptake of small peptides.
Gene References into Functions
  1. some mutants of Ptr2 that are dysfunctional in dipeptide uptake were still competent to transport BlaS. Mouse-derived oligopeptide transporter PepT1 conferred BlaS sensitivity in the S. cerevisiae ptr2 mutant PMID: 27916534
  2. Ptr2 mutants of the peptide-binding site exhibited severe defects in peptide import and were subject to Rsp5-dependent degradation suggesting that Ptr2 undergoes quality control that renders Ptr2 subject to efficient ubiquitination and degradation. PMID: 25172766
  3. The substrate multispecificity of PTR2 indicates that it has an important role in the preferential uptake of vital amino acids. PMID: 24060756
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
PTR2/POT transporter (TC 2.A.17) family
Database Links

KEGG: sce:YKR093W

STRING: 4932.YKR093W

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