PUS4 Antibody

Code CSB-PA341771XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PUS4 Polyclonal antibody
Uniprot No.
Target Names
PUS4
Alternative Names
PUS4 antibody; YNL292W antibody; N0480 antibody; tRNA pseudouridine synthase 4 antibody; EC 5.4.99.25 antibody; tRNA pseudouridine(55) synthase antibody; Psi55 synthase antibody; tRNA pseudouridylate synthase 4 antibody; tRNA-uridine isomerase 4 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PUS4 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. Also catalyzes pseudouridylation of mRNAs with the consensus sequence 5'-GGUUCRA-3'.
Gene References into Functions
  1. Pus4 and App1 dramatically inhibit Brome Mosaic Virus systemic spread in plants, reduce BMV genomic plus-strand RNA accumulation, and prevent the encapsidation of a BMV RNA. PMID: 17360619
Subcellular Location
Nucleus. Mitochondrion.
Protein Families
Pseudouridine synthase TruB family
Database Links

KEGG: sce:YNL292W

STRING: 4932.YNL292W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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