pyrG Antibody

Code CSB-PA006176XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) pyrG Polyclonal antibody
Uniprot No.
Target Names
pyrG
Alternative Names
pyrG antibody; b2780 antibody; JW2751 antibody; CTP synthase antibody; EC 6.3.4.2 antibody; Cytidine 5'-triphosphate synthase antibody; Cytidine triphosphate synthetase antibody; CTP synthetase antibody; CTPS antibody; UTP--ammonia ligase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) pyrG protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
Gene References into Functions
  1. results depict a novel product inhibition strategy in which shared substrate & product moieties bind to a single subsite while specificity is conferred by separate subsites; this allows for independent adaptation of UTP & CTP binding affinities PMID: 16216072
  2. The conformational change associated with binding ATP may be transmitted through the L10-alpha11 structural unit (residues 297-312) and thereby mediate effects on the glutaminase activity of CTPS. PMID: 16427816
Subcellular Location
Cytoplasm.
Protein Families
CTP synthase family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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