qvr Antibody

Datasheet

Code	CSB-PA480381XA01DLU
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) qvr Polyclonal antibody

Uniprot No.

B5A5T4

Target Names

qvr

Alternative Names

qvr antibody; sss antibody; CG33472 antibody; Protein quiver antibody; Protein sleepless antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) qvr protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation. Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability.

Gene References into Functions

QVR/SSS, and by extension perhaps other Ly6 proteins, target effector molecules using limited protein motifs. PMID: 26828958
role in controlling excitability and synaptic transmission in fundamental processes of the nervous system such as sleep PMID: 24613312
Day-night cycles and the sleep-promoting factor, Sleepless, affect stem cell activity in the Drosophila testis. PMID: 24516136
This study demonstrated that SLEEPLESS (SSS) protein modulates Shaker channel activity, possibly through a direct interaction at the plasma membrane. PMID: 21813698
Two different functional states of Shaker I(A) current are observed in qvr larval muscles, as reflected by two distinct components differing in their kinetics of recovery from inactivation and sensitivity to a potassium channel blocker. PMID: 20429677
The sleepless (sss) gene is required for sleep in Drosophila. It is proposed that SLEEPLESS is a signaling molecule that connects sleep drive to lowered membrane excitability. PMID: 18635795

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Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Quiver family

Tissue Specificity

Enriched in brain and head.

Database Links

KEGG: dme:Dmel_CG33472

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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qvr Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background