RAD23 Antibody

1. Rad4-Rad23 forms non-motile complexes or conducts a one-dimensional search for DNA lesions via either random diffusion or constrained motion. PMID: 27720644
2. these studies are consistent with a model in which Rad23p partners with the deglycosylating enzyme Png1p to reduce manganese toxicity through proteosomal degradation of glycosylated substrate(s). PMID: 22281500
3. C-terminal UBA domain of Rad23 ubiquitin receptor protects it by preventing initiation of protein degradation at the proteasome. PMID: 21304520
4. Rad23 escapes degradation because it lacks a proteasome initiation region. PMID: 21304521
5. Role of Rad23 protein in DNA repair. PMID: 15545636
6. Rad23 stabilizes Rad4 from degradation during nucleotide excision-repair. PMID: 15601997
7. Results reveal that Rad23 and Ddi1 interact with each other by using UBL/UBA domain interactions in a manner that does not preclude their interaction with ubiquitin. PMID: 16405905
8. determined that hHR23A and hHR23B could be co-purified with unique proteolytic and stress-responsive factors from human breast cancer tissues, indicating that they have unique functions in vivo PMID: 16712842
9. Snf6 and Snf5, two subunits of the SWI/SNF chromatin-remodeling complex in Saccharomyces cerevisiae, copurify with the NER damage-recognition heterodimer Rad4-Rad23. This interaction between SWI/SNF and Rad4-Rad23 is stimulated by UV irradiation. PMID: 17013386
10. recognition of polyubiquitin chains by Rad23 promotes its shuttling to the proteasome in vivo PMID: 17360968
11. Mutations in the hydrophobic core of ubiquitin affect its recognition by RAD23. PMID: 18054791
12. Rad23, originally identified as an important factor involved in the recognition of DNA lesions, also plays a central role in targeting ubiquitylated proteins for proteasomal degradation [Review] PMID: 19223247

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KEGG: sce:YEL037C

STRING: 4932.YEL037C