rad24 Antibody

Code CSB-PA337162XA01SXV
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) rad24 Polyclonal antibody
Uniprot No.
Target Names
rad24
Alternative Names
rad24 antibody; SPAC8E11.02c antibody; DNA damage checkpoint protein rad24 antibody
Raised in
Rabbit
Species Reactivity
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen
Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) rad24 protein
Immunogen Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Acts in cell cycle and stress checkpoint signaling by sequestering signal transducers regulated by the checkpoints. Required for the DNA damage checkpoint that ensures that DNA damage is repaired before mitosis is attempted. During environmental stress, sequesters srk1-phosphorylated cdc25 in the cytoplasm to delay the G2/M transition. Sequesters byr2 in the cytoplasm to prevent its translocation to the plasma membrane. Sequesters ran1/pat1-phosphorylated mei2 from its non-coding RNA activators (including meiRNA), to prevent meiotic induction in vegetative cells and to regulate meiosis I.
Gene References into Functions
  1. The loss of rad24 in ssp1(-) cells reduces the severity of hyperosmotic stress response and relieves mitotic delay. PMID: 24451546
  2. Rad24p-mediated cytoplasmic retention of Clp1p/Flp1p is important for cell viability upon stress to the cell division apparatus. PMID: 16085489
  3. data presented here show that two elements of fission yeast DNA structure checkpoints, Rad26 and Rad24, define a pathway that responds to microtubule destabilizing conditions PMID: 16930478
  4. The 14-3-3 protein Rad24p is involved in negative control of pho1 gene expression in Schizosaccharomyces pombe. PMID: 17173334
  5. Identification of sam4 as an allele of rad24. PMID: 19584544

Show More

Hide All

Subcellular Location
Cytoplasm.
Protein Families
14-3-3 family
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1