RAD34 Antibody

Code CSB-PA971440XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RAD34 Polyclonal antibody
Uniprot No.
Target Names
RAD34
Alternative Names
RAD34 antibody; YDR314C antibody; DNA repair protein RAD34 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RAD34 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in nucleotide excision repair (NER) of damaged ribosomal DNA (rDNA). Required for the repair of the RNA polymerase I-transcribed strand of rDNA.
Gene References into Functions
  1. the two homologous proteins Rad4 and YDR314C are both involved in nucleotide excision repair and probably have a similar function, but operate at different loci in the genome and are unable to replace each other PMID: 15916602
  2. Data show that Rad4p is essential for repair in the intergenic spacer and the transcription initiation site, while Rad34p is necessary for transcription-coupled NER that starts about 40 nucleotides downstream of the transcription initiation site. PMID: 18936173
Subcellular Location
Nucleus.
Protein Families
XPC family
Database Links

KEGG: sce:YDR314C

STRING: 4932.YDR314C

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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