RAD54 Antibody

1. ad51-mediated recombination occurring in the absence of Hed1 phosphorylation results in a significant increase in non-exchange chromosomes despite wild-type levels of crossovers, confirming previous results indicating a defect in crossover assurance. We propose that Rad51 function in meiosis is regulated in part by the coordinated phosphorylation of Rad54 and Hed1 by Mek1 PMID: 27483004
2. Our study identified a novel sequence motif critical for Rad54 function and showed that even perfect matches to the PIP box consensus may not necessarily identify PCNA interaction sites. PMID: 24358152
3. Rad54 acts as an hDNA pump that drives D loop formation while simultaneously removing Rad51 from hDNA, consolidating both ATP-dependent activities of Rad54 into a single mechanistic step. PMID: 24486020
4. SN specifically targets the RAD54 ATPase, but not DNA binding, through direct interaction with RAD54 and generation of reactive oxygen species. PMID: 24043618
5. functional importance of the N-terminal Rad51 interaction domain of Rad54 PMID: 15465810
6. The trans-species compatibility of Rad54 functions, is reported. PMID: 18430956
7. Rad54 dissociates Rad51 protein bound to the heteroduplex DNA after DNA strand invasion. PMID: 19074197
8. Studies identified an additional role for Mek1 in inhibiting the activity of the Rad51 recombinase through phosphorylation of its binding partner, Rad54. PMID: 19917248

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KEGG: sce:YGL163C

STRING: 4932.YGL163C