rae-1 Antibody

Code CSB-PA821908XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans rae-1 Polyclonal antibody
Uniprot No.
Target Names
rae-1
Alternative Names
rae-1 antibody; npp-17 antibody; F10G8.3 antibody; mRNA export factor rae-1 antibody; Nuclear pore complex protein 17 antibody; Nucleoporin-17 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans rae-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. It is specifically important for nuclear mRNA export. Has a role in neuronal development, where it acts downstream of rpm-1 to control axon termination and synapse formation in anterior lateral microtubule (ALM) and posterior lateral microtubule (PLM) mechanosensory neurons.
Subcellular Location
Nucleus, nuclear pore complex. Nucleus. Cell projection, axon. Cell junction, synapse.
Protein Families
WD repeat rae1 family
Tissue Specificity
Expressed along the ventral and dorsal nerve cords.
Database Links

KEGG: cel:CELE_F10G8.3

STRING: 6239.F10G8.3.2

UniGene: Cel.17126

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