RAS2 Antibody

1. Fructose-1,6-bisphosphate is a potent activator of Ras2 in permeabilized yeast cells, likely acting through Cdc25. PMID: 29030545
2. Dominant negative Ras2 mutants survive lethal stressors following mild heat shock PMID: 27939892
3. Active Ras accumulates in internal membranes and mitochondria, both when cells are growing on glucose medium or are starved. PMID: 23127800
4. The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate. PMID: 22904317
5. RAS2 regulates spore formation via Ras/cyclic AMP/protein kinase A pathway. PMID: 22660623
6. Ras2 protein acts as a target of the glucose feedback-inhibition mechanism PMID: 15339905
7. We show that a RAS2(val19) mutant that exhibits elevated levels of Ras/PKA signaling activity is unable to grow on media with galactose as the sole source of carbon. PMID: 16292676
8. role of Ras2p as a powerful modulator of metabolism during growth on a non-fermentable carbon source PMID: 16832579
9. Val19 mutation of RAS2 (overactive) abrogated ATP/ADP carrier activity in S. cerevisiae cells, leading to reduced prolif. and accel. senescence via two ROS-dep. routes, PKA-dependent and -independent ones. PMID: 18081742

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KEGG: sce:YNL098C

STRING: 4932.YNL098C