RBG8 Antibody

Datasheet

Code	CSB-PA311760XA01DOA
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Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) RBG8 Polyclonal antibody

Uniprot No.

Q03251

Target Names

RBG8

Alternative Names

RBG8 antibody; CCR1 antibody; GR-RBP8 antibody; GRP8 antibody; At4g39260 antibody; T22F8.160 antibody; Glycine-rich RNA-binding protein 8 antibody; AtGR-RBP8 antibody; AtRBG8 antibody; Glycine-rich protein 8 antibody; AtGRP8 antibody; Protein COLD antibody; CIRCADIAN RHYTHM antibody; AND RNA BINDING 1 antibody; Protein CCR1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana RBG8 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Plays a role in RNA transcription or processing during stress. Binds RNAs and DNAs sequence with a preference to single-stranded nucleic acids. Involved in mRNA alternative splicing of numerous targets by modulating splice site selection. Negatively regulates the circadian oscillations of its own transcript as well as RBG7 transcript. Forms an interlocked post-transcriptional negative feedback loop with the RBG7 autoregulatory circuit. Both proteins negatively autoregulate and reciprocally crossregulate by binding to their pre-mRNAs and promoting unproductive splicing coupled to degradation via the NMD pathway. Target of the Pseudomonas syringae type III effector HopU1.

Gene References into Functions

the yield penalty of ccr1 mutants was not caused by ferulic acid accumulation but was (largely) the consequence of collapsed vessels. PMID: 29158331
Data show that AtGRP8 binds to AtGRP7 and levels of the alternatively spliced AtGRP8 transcripts that contain premature termination codons are strongly elevated in mutants impaired in the nonsense-mediated decay (NMD) components UPF1 or UPF3. PMID: 17924945
AtGRP8 binds to its own and the AtGRP7 pre-mRNA, suggesting that this interaction is relevant for the splicing regulation. PMID: 18987006

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

GR-RBP family

Tissue Specificity

Ubiquitous.

Database Links

KEGG: ath:AT4G39260

STRING: 3702.AT4G39260.1

UniGene: At.23968

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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RBG8 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background