rbn Antibody

Datasheet

Code	CSB-PA364228XA01ENV
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Product Details

Full Product Name

Rabbit anti-Escherichia coli (strain K12) rbn Polyclonal antibody

Uniprot No.

P0A8V0

Target Names

rbn

Alternative Names

rbn antibody; elaC antibody; rnz antibody; b2268 antibody; JW2263 antibody; Ribonuclease BN antibody; RNase BN antibody; EC 3.1.-.- antibody; Ribonuclease Z homolog antibody; RNase Z homolog antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli (strain K12)

Immunogen

Recombinant Escherichia coli (strain K12) rbn protein

Immunogen Species

Escherichia coli (strain K12)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities, depending on the nature of the substrate and of the added divalent cation, and on its 3'-terminal structure. Can process the 3' termini of both CCA-less and CCA-containing tRNA precursors. CCA-less tRNAs are cleaved endonucleolytically after the discriminator base, whereas residues following the CCA sequence can be removed exonucleolytically or endonucleolytically in CCA-containing molecules. Does not remove the CCA sequence. May also be involved in the degradation of mRNAs. In vitro, hydrolyzes bis(p-nitrophenyl)phosphate and thymidine-5'-p-nitrophenyl phosphate.

Gene References into Functions

These data indicate that RNase BN plays an important role in determining levels of the global transcription regulator, 6S RNA, throughout the growth cycle. PMID: 27875308
metal selectivity of ZiPD only partially relies on first shell metal ligands PMID: 15324305
A ZiPD exosite is identified that guides physiological substrate recognition in the ZiPD/ElaC protein family. PMID: 15699034
the RNase Z homologue encoded by Escherichia coli elaC gene is RNase BN PMID: 15764599
the first crystal structure of ZiPD determined by multiple anomalous diffraction at a resolution of 2.9 A PMID: 16452444
These results suggest a potentially important new role for the RNase Z family of proteins in RNA metabolism, particularly in organisms lacking RNase E. PMID: 16629673

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Protein Families

RNase Z family, RNase BN subfamily

Database Links

KEGG: ecj:JW2263

STRING: 316407.85675333

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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rbn Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background