RBP3 Antibody

Code CSB-PA019482ZA01BO
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Product Details

Full Product Name
Rabbit anti-Bos taurus (Bovine) RBP3 Polyclonal antibody
Uniprot No.
Target Names
RBP3
Alternative Names
RBP3 antibody; Retinol-binding protein 3 antibody; Interphotoreceptor retinoid-binding protein antibody; IRBP antibody; Interstitial retinol-binding protein antibody; Protein 7S antibody
Raised in
Rabbit
Species Reactivity
Bos taurus
Immunogen
Recombinant Bos taurus RBP3 protein
Immunogen Species
Bos taurus (Bovine)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.
Gene References into Functions
  1. IRBP is able to bind a variety of carotenoids at an affinity comparable to retinoids and with much stronger affinity than any fatty acid tested. PMID: 23876239
  2. In mouse immunization studies Ehrlichia canis amino acid sequence 44-59 is identified as a candidate mimicry epitope for interphotoreceptor retinoid-binding protein (IRBP) 201-216 and is capable of preventing ocular inflammation. PMID: 24029580
  3. KLF15 binds to multiple 9 bp consensus sites in the Rhodospin and IRBP promoters including the CRS-1 and G-rich repressor elements. PMID: 15963234
  4. Localized to interphotoreceptor matrix, where it is available for binding and transport of visual cycle retinoids. PMID: 17200663
Subcellular Location
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Note=Interphotoreceptor matrix that permeates the space between the retina and the contiguous layer of pigment epithelium cells.
Protein Families
Peptidase S41A family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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