rcan-1 Antibody

Code CSB-PA346484XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans rcan-1 Polyclonal antibody
Uniprot No.
Target Names
rcan-1
Alternative Names
rcan-1 antibody; dscr1l antibody; rcn-1 antibody; F54E7.7 antibody; Calcipressin-like protein antibody; Down syndrome candidate region 1-like protein antibody; Regulator of calcineurin antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans rcan-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Inhibits tax-6/calcineurin A phosphatase activity and thereby negatively regulates calcineurin-mediated functions. Plays a role in modulating temperature-dependent calcium responses in AFD neurons and in addition, also negatively regulates thermotaxis in a tax-6-dependent manner in AFD neurons. In response to changes in intracellular calcium levels may also regulate nuclear translocation of transcriptional regulators such as crtc-1. May play a role in regulating body size. Plays a role in male tail tip morphogenesis.
Protein Families
RCAN family
Tissue Specificity
Expressed in lateral hypodermal cells, marginal cells of the pharynx, vulva epithelial cells, ventral and dorsal nerve cords and commissures and various neurons in the anterior and posterior regions. Expressed in male tail structures including the diagona
Database Links

KEGG: cel:CELE_F54E7.7

STRING: 6239.F54E7.7

UniGene: Cel.19514

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