Rcc1 Antibody

Datasheet

Code	CSB-PA019505XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Rcc1 Polyclonal antibody

Uniprot No.

P25171

Target Names

Rcc1

Alternative Names

Rcc1 antibody; Bj1 antibody; CG10480 antibody; Regulator of chromosome condensation antibody; Chromatin-binding protein Bj1 antibody; Regulator of chromosome condensation 1 ortholog antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Rcc1 protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to chromatin.

Gene References into Functions

the Bj1 RanGEF promotes Prospero nuclear export and neuroblast self-renewal PMID: 25312250
crystal structure of a complex of Drosophila RCC1 and the nucleosome core particle at 2.9 A resolution, providing an atomic view of how a chromatin protein interacts with the histone and DNA components of the nucleosome PMID: 20739938
Data show that dRCC1 is required for nuclear import of nuclear localization signal sequence (NLS)-carrying cargo molecules and for cell proliferation and/or survival during germline, eye and wing development and that dRCC1 appears to facilitate apoptosis. PMID: 15136144

Subcellular Location

Nucleus. Cytoplasm. Note=Becomes dispersed throughout the cytoplasm during mitosis. Is associated with chromatin throughout mitosis.

Database Links

KEGG: dme:Dmel_CG10480

STRING: 7227.FBpp0076782

UniGene: Dm.8023

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Rcc1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background