rcsC Antibody

Code CSB-PA448898XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) rcsC Polyclonal antibody
Uniprot No.
Target Names
rcsC
Alternative Names
rcsC antibody; b2218 antibody; JW5917/JW5920 antibody; Sensor histidine kinase RcsC antibody; EC 2.7.13.3 antibody; Capsular synthesis regulator component C antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) rcsC protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. RcsC has also phosphatase activity. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.
Gene References into Functions
  1. RcsF also interacts with the periplasmic domain of the innermembrane-localized histidine kinase RcsC. PMID: 28691662
  2. a number of signals that lead to activation of the phosphorelay require both RcsF and RcsC PMID: 16166540
  3. Results describe the solution structure of the RcsC C terminus, possessing a phosphoreceiver domain (RcsC-PR) and a region previously described as a long linker between the histidine kinase domain of RcsC (RcsC-HK) and the RcsC-PR. PMID: 17005198
Subcellular Location
Cell inner membrane; Multi-pass membrane protein.
Protein Families
RcsC family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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