Protein Rex Antibody

Code CSB-PA768043XA01HQL
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Product Details

Uniprot No.
Alternative Names
Protein Rex antibody; Rev homolog antibody; Rex-2 antibody
Raised in
Rabbit
Species Reactivity
Human T-cell leukemia virus 2 (HTLV-2)
Immunogen
Recombinant Human T-cell leukemia virus 2 (HTLV-2) Protein Rex protein
Immunogen Species
Human T-cell leukemia virus 2 (HTLV-2)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Rex escorts unspliced gag-pro-pol and singly spliced env mRNAs out of the nucleus of infected cells. These mRNAs carry a recognition sequence called Rex responsive element (RxRE or XRE) located at the 3' region of the long terminal repeat (LTR). This function is essential since most HTLV proteins are translated from unspliced or partially spliced pre-mRNAs that cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.
Gene References into Functions
  1. Rex-2 has a novel C-terminal inhibitory domain that regulates functional activity and is positively regulated through phosphorylation. PMID: 19279097
  2. The authors identified six phosphorylation sites in p26(Rex) at Thr-19, Ser-117, Ser-125, Ser-151, Ser-153, and Thr-164. PMID: 19553333
Subcellular Location
Host nucleus, host nucleolus. Host cytoplasm.
Protein Families
Deltaretrovirus Rex protein family
Database Links

KEGG: vg:1491945

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