Rga Antibody

Code CSB-PA850066XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Rga Polyclonal antibody
Uniprot No.
Target Names
Rga
Alternative Names
Rga antibody; Not2 antibody; CG2161 antibody; Regulator of gene activity antibody; Protein regena antibody; CCR4-NOT transcription complex subunit 2 homolog antibody; CNOT2 antibody; Not2 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Rga protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Essential for viability. Acts as a suppressor of position effect variegation (PEV) at the white locus and regulates the expression of several unrelated genes. Plays a role in germline stem cell differentiation in the ovaries.
Subcellular Location
Cytoplasm.
Protein Families
CNOT2/3/5 family
Tissue Specificity
Expressed in heterogeneous levels between adjacent germline stem cells (at protein level).
Database Links

KEGG: dme:Dmel_CG2161

STRING: 7227.FBpp0078390

UniGene: Dm.2486

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