Name: RGD1 Antibody
Brand: CUSABIO
SKU: CSB-PA336439XA01SVG

Product Details

Full Product Name	Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RGD1 Polyclonal antibody
Uniprot No.	P38339
Target Names	RGD1
Alternative Names	RGD1 antibody; YBR260C antibody; YBR1728 antibody; RHO GTPase-activating protein RGD1 antibody; RhoGAP antibody; Related GAP domain protein 1 antibody
Raised in	Rabbit
Species Reactivity	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen	Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RGD1 protein
Immunogen Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables	① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee	① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Lead Time	Made-to-order (14-16 weeks)

Target Background

Function (From Uniprot)	GTPase activating protein of RHO3 and RHO4. Acts in concert with MID2 in cell integrity, which is functionally linked to the PKC pathway. Involved in various stress responses. Required at low pH for activation of the PKC pathway. Important during mating response.
Gene References into Functions	demonstrate that Rgd1p is phosphorylated by the Aurora B like kinase Ipl1 and observe that loss of Ipl1 function leads to a new Rgd1p distribution in a small part of the cell population PMID: 23454383 Rgd1p colocalizes with a subset of the post-golgi marker Sec2p and is transported to the bud tip. PMID: 22447923 The authors propose that Tos2p, a protein involved in polarized growth and most probably associated with the plasma membrane, modulates the action of Rgd1p and Rho3p in Saccharomyces cerevisiae. PMID: 21143383 the first evidences for a specific interaction between a RhoGAP domain (the RhoGAP domain of Rgd1p) and phosphoinositides were provided. PMID: 21215255 The rgd1Delta strain is sensitive to low pH, and Rgd1p activates the PKC pathway in an acidic environment PMID: 16087742 Phosphoinositides both regulate the recruitment and trafficking of Rgd1p to membranes via the F-BAR domain and specifically stimulate GTPase-activating protein activity PMID: 18845541 Show More Hide All
Subcellular Location	Cytoplasm. Note=Bud and bud neck. During isotropic bud growth in the G1 and S phases, detected at the bud tip. During cytokinesis, undetectable at the bud tip and localized at the bud neck only.
Database Links	KEGG: sce:YBR260C STRING: 4932.YBR260C

CloseMessage

Product >> Product Name：
Product >> Code：
Product >> Size：
Name： *
Email： *
Phone：
We recommend you to leave your phone number because occasionally our emails get flagged by spam filters. We would not disclose any of your private information to any third party.
Question/Comment： *
Your Region： *
Country State：
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
Check Code：

RGD1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background

CloseMessage

Code	CSB-PA336439XA01SVG
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat