rig-3 Antibody

Code CSB-PA794038XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans rig-3 Polyclonal antibody
Uniprot No.
Target Names
rig-3
Alternative Names
rig-3 antibody; C53B7.1 antibody; Neuronal immunoglobulin domain-containing protein rig-3 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans rig-3 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cell surface protein which plays a role in the plasticity of cholinergic synapses at neuromuscular junctions and in the polarity of the mechanosensory neuron ALM, possibly by antagonizing Wnt signaling.
Gene References into Functions
  1. RIG-3 inhibits Wnt/LIN-44 signaling pathway through interaction with CAM-1. PMID: 28515212
  2. results identify RIG-3 as a regulator of Wnt signaling, and suggest that RIG-3 has an anti-plasticity function preventing activity-induced changes in postsynaptic receptor fields. PMID: 21745641
Subcellular Location
Cell projection, axon. Cell junction, synapse. Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity
Expressed in the cholinergic motor neurons AS, VA and DA in the ventral nerve cord and in the mechanosensory ALM neurons in the midbody.
Database Links

KEGG: cel:CELE_C53B7.1

STRING: 6239.C53B7.1

UniGene: Cel.6793

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