RNR1 Antibody

Code CSB-PA890356XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) RNR1 Polyclonal antibody
Uniprot No.
Target Names
RNR1
Alternative Names
RNR1 antibody; DPD2 antibody; At2g21790 antibody; F7D8.11 antibody; Ribonucleoside-diphosphate reductase large subunit antibody; EC 1.17.4.1 antibody; Protein DEFECTIVE IN POLLEN DNA DEGRADATION 2 antibody; Ribonucleoside-diphosphate reductase R1 subunit antibody; AtRNR1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana RNR1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. Ribonucleotide reductase (RNR) complex function is essential for efficient organellar DNA degradation in pollen. Involved in chloroplast division.
Gene References into Functions
  1. The cooperative activity of two 3'-->5' exoribonucleases in chloroplast mRNA 3' end maturation, and support the hypothesis that RNR1 plays a significant role in the destabilization of mRNAs unprotected by ribosomes. PMID: 23061883
  2. Data show that the defects in ribonucleotide reductase DPD2 (At2g21790) indirectly compromise the activity of DPD1 nuclease (At5g26940) in plastids, suggesting a different regulation of organellar DNA degradation in pollen. PMID: 22239102
Subcellular Location
Cytoplasm.
Protein Families
Ribonucleoside diphosphate reductase large chain family
Tissue Specificity
Highly expressed in actively growing tissues such as young leaves, shoot apices, inflorescences and carpels. Very low expression in cotyledons, adult and cauline leaves and senescent leaves.
Database Links

KEGG: ath:AT2G21790

STRING: 3702.AT2G21790.1

UniGene: At.115

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