suc22 Antibody

Code CSB-PA339706XA01SXV
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Product Details

Full Product Name
Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) suc22 Polyclonal antibody
Uniprot No.
Target Names
suc22
Alternative Names
suc22 antibody; SPBC25D12.04 antibody; Ribonucleoside-diphosphate reductase small chain antibody; EC 1.17.4.1 antibody; Ribonucleotide reductase small subunit antibody
Raised in
Rabbit
Species Reactivity
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen
Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) suc22 protein
Immunogen Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Gene References into Functions
  1. Spd1p inhibits fission yeast ribonucleotide reductase (RNR) activity by binding to Cdc22p, which is the large subunit of RNR, and not to Suc22p, which is the small subunit of RNR. PMID: 16317005
  2. Spd1 inhibits ribonucleotide reductase (RNR) activity by anchoring the small RNR subunit Suc22 in the nucleus. PMID: 12695334
Subcellular Location
Nucleus. Cytoplasm. Note=Localization to the cytoplasm is CSN- and checkpoint-dependent and is required for an efficient DNA damage response.
Protein Families
Ribonucleoside diphosphate reductase small chain family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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