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rn Antibody

Datasheet
Code CSB-PA895146XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) rn Polyclonal antibody
Uniprot No.
Q9VI93
Target Names
rn
Alternative Names
rn antibody; roe antibody; CG32466 antibody; Zinc finger protein rotund antibody; Zinc finger protein roughened eye antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) rn protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcription factor involved in imaginal disks development. Isoform rn is required in the wings, antenna, haltere, proboscis and legs disks, while isoform roe is required in the eye disk. Together with nab corepressor, it is involved in the initiation and maintenance of wingless (wg) expression in the wing hinge, by limiting the expression of wg to this compartment. Also required for the epithelial-mesenchymal transition branch of basolateral junctions signaling.
Gene References into Functions
  1. The Drosophila rotund gene codes for two distinct zinc finger proteins. PMID: 11874922
  2. Squeeze and Rotund are regulated by Nab and have roles in Drosophila development PMID: 17428824
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Isoform rn and isoform roe are expressed in non-overlapping domains in the larval imaginal disks. Isoform rn is first expressed during the early third larval instar in the leg, wing, haltere and antennal part of the eye-antennal imaginal disk. It is obser
Database Links

KEGG: dme:Dmel_CG42277

STRING: 7227.FBpp0303173

UniGene: Dm.5644

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