RNASE4 Antibody

Code CSB-PA019796ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RNASE4 Polyclonal antibody
Uniprot No.
Target Names
RNASE4
Alternative Names
RAB1 antibody; Ribonuclease 4 antibody; Ribonuclease A B1 antibody; ribonuclease A family member 4 antibody; Ribonuclease; RNase A family; 4 antibody; RNAS4_HUMAN antibody; RNase 4 antibody; RNASE4 antibody; RNS4 antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens
Immunogen
Recombinant Homo sapiens RNASE4 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
This RNase has marked specificity towards the 3' side of uridine nucleotides.
Gene References into Functions
  1. RNASE4, STAT3, and miRNA-124 may have a regulatory association with the pathological mechanisms in Huntington's disease. PMID: 29328442
  2. Data show that the transcription of angiogenin (ANG) and ribonuclease 4 (RNASE4) promoter is influenced by RNA polymerase III (Pol III) elements and could be differentially regulated by an intragenic CCCTC binding factor (CTCF)-dependent chromatin loop. PMID: 24659782
  3. RNASE4 not only stimulates the formation of neurofilaments from mouse embryonic cortical neurons, but also protects hypothermia-induced degeneration PMID: 23143660
Subcellular Location
Secreted.
Protein Families
Pancreatic ribonuclease family
Database Links

HGNC: 10047

OMIM: 601030

KEGG: hsa:6038

STRING: 9606.ENSP00000381081

UniGene: Hs.283749

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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