hoe-1 Antibody

Code CSB-PA525010XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans hoe-1 Polyclonal antibody
Uniprot No.
Target Names
hoe-1
Alternative Names
hoe-1 antibody; E04A4.4 antibody; Ribonuclease Z antibody; RNase Z antibody; EC 3.1.26.11 antibody; CeELAC2 antibody; Homolog of ELAC2 protein 1 antibody; tRNA 3 endonuclease antibody; tRNase Z antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans hoe-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Involved in germline proliferation. May be required for both mitosis and meiosis in germ cells.
Gene References into Functions
  1. required for hyperproliferation phenotypes seen with mutations in three different genes, suggesting it may be generally required for germline proliferation PMID: 14729485
Subcellular Location
Nucleus.
Protein Families
RNase Z family
Tissue Specificity
Highly expressed in the germline.
Database Links

KEGG: cel:CELE_E04A4.4

STRING: 6239.E04A4.4a

UniGene: Cel.5155

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