rodZ Antibody

Code CSB-PA329725XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) rodZ Polyclonal antibody
Uniprot No.
Target Names
rodZ
Alternative Names
rodZ antibody; yfgA antibody; b2516 antibody; JW2500 antibody; Cytoskeleton protein RodZ antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) rodZ protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
Gene References into Functions
  1. the membrane protein RodZ regulates the biophysical properties of MreB and alters the spatial organization of E. coli cell-wall growth. PMID: 29599448
  2. The data suggest that RodZ promotes the assembly of geometrically-localized MreB polymers that lead to the growth of uniform E. coli cylinders. PMID: 30022070
  3. Results suggest that MreB binding to the cytoplasmic domain of RodZ causes structural changes in the disordered periplasmic domain of RodZ; also found that the disordered domain of RodZ contributes to fine-tune rod shape in E. coli. PMID: 29480545
  4. Data show that actin homolog MreB rotates because cytoplasmic MreB filaments are coupled to periplasmic cell wall synthesis through the transmembrane protein RodZ, which acts as a transmembrane linker. PMID: 26396257
  5. These are the first data that suggest that rodZ plays an essential role in DNA acquisition. PMID: 22497891
  6. RodZ is not absolutely required for the elongation of the lateral cell wall and the synthesis of functional flagella. PMID: 20528937

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Subcellular Location
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein Families
RodZ family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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