RRP6L1 Antibody

Datasheet

Code	CSB-PA207330XA01DOA
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) RRP6L1 Polyclonal antibody

Uniprot No.

Q0WVE8

Target Names

RRP6L1

Alternative Names

RRP6L1 antibody; At1g54440 antibody; F20D21.26 antibody; Protein RRP6-like 1 antibody; AtRRP6L1 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana RRP6L1 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as an important epigenetic regulator through multiple silencing mechanisms. Involved in transcriptional gene silencing (TGS). Plays a role for DNA methylation in the RNA-directed DNA methylation (RdDM) pathway. Contributes to the methylation status of the retrotransposon SN1. Required for DNA methylation only at a subset of RdDM target loci. Plays a regulatory role in RdDM through retention of non-coding RNAs (ncRNAs) in normal cells. Helps to retain Pol V-transcribed RNAs in chromatin to enable their scaffold function and is required for genome-wide Pol IV-dependent siRNA (24 nt siRNA) production that may involve retention of Pol IV transcripts. Involved in association with RRP6L2 in the silencing of the solo LTR locus. Controls levels of ncRNAs from the solo LTR locus. Seems to function independently of the RdDM pathway. Functions redundantly with RRP6L2 in the regulation of FLC locus. Participates in the maintenance of trimethylated 'Lys-27' (H3K27me3) at FLC locus via the regulation of antisense long non-coding RNAs (lncRNAs) and the regulation of diverse antisense RNAs derived from the FLC locus. Seems not involved in the exosomal RNA degradation. Can complement the growth defect of a yeast mutant lacking RRP6 exonuclease.

Gene References into Functions

AtRRP6L1 plays an important role in transcriptional gene silencing in Arabidopsis. [AtRRP6L1] PMID: 24719467
AtRRP6L1 functions in epigenetic regulation by helping with the retention of noncoding RNAs in normal cells. PMID: 24726328

Subcellular Location

Nucleus. Nucleus, nucleoplasm.

Database Links

KEGG: ath:AT1G54440

STRING: 3702.AT1G54440.2

UniGene: At.37214

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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