RPH1 Antibody

1. led to the identification of Rph1 as a master transcriptional regulator of autophagy PMID: 25751780
2. Rph1/KDM4 mediates nutrient-limitation signaling that leads to the transcriptional induction of autophagy. PMID: 25660547
3. activity of Rph1 is not essential for its role in the transcriptional response to nutrient signaling PMID: 24999627
4. Our findings confirm the regulatory role of Rph1 as a transcriptional repressor and reveal that Rph1 might be a regulatory node connecting different signaling pathways responding to environmental stresses. PMID: 23985319
5. these results show that of the JmjC-containing proteins, Rph1 is the demethylase that is specific for histone H3K36 trimethylation during transcription elongation in vivo. PMID: 21684259
6. Results demonstrates that the histone demethylase Rph1 is associated with a specific chromatin locus and modulates histone modifications to repress a DNA damage responsive gene under control of damage checkpoint signaling. PMID: 21296759
7. Results identify Rph1, a JmjC-domain-containing histone demethylase, which can specifically demethylate H3K36 tri- and dimethyl modification states. PMID: 17371840

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KEGG: sce:YER169W

STRING: 4932.YER169W