RPO41 Antibody

1. Rpo41-Mtf1 is an attractive candidate for serving as the primase to initiate lagging strand DNA synthesis during normal replication and/or to restart stalled replication from downstream ssDNA. PMID: 27311715
2. results thus indicate that the PPR motifs do not play an essential role in the function of the NTE domain of the mitochondrial RNA polymerase Rpo41p. PMID: 27908235
3. Herein the authors found that Rpo41 transcribes RNAs that can be extended by Mip1 on single and double-stranded DNA. PMID: 26184436
4. The study examined a series of N-terminal deletion mutants of yeast mitochondrial RNA polymerase, Rpo41, and found that the N-terminal region does not abolish the effects of Mtf1; rather it contributes directly to enzyme catalysis. PMID: 26332125
5. This study identifies the importance of the +1+2 AA promoter sequence interactions with Rpo41-Mtf1 in dictating pre-transcribing complex formation, which regulates the binding of initiating NTPs and the catalytic efficiency of transcription initiation. PMID: 25249624
6. While Rpo41 induces a slight bend upon binding both the DNAs, addition of the Mtf1 results in severe bending of the promoter and unbending of the non-promoter DNA PMID: 21911502
7. Data show that he promoter DNA is sandwiched between Mtf1 and Rpo41 in the structural model. PMID: 20008320
8. Data show that both Rpo41p and Mtf1p contact with promoter DNA. PMID: 19920143
9. core mitochondrial RNA polymerase (Rpo41) has the intrinsic ability to initiate from promoters without its specificity factor (Mtf1) PMID: 15342628

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KEGG: sce:YFL036W

STRING: 4932.YFL036W