rraA Antibody

Code CSB-PA359177XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) rraA Polyclonal antibody
Uniprot No.
Target Names
rraA
Alternative Names
rraA antibody; menG antibody; yiiV antibody; b3929 antibody; JW3900 antibody; Regulator of ribonuclease activity A antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) rraA protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
Gene References into Functions
  1. The phosphate sensor is required for efficient autoregulation of RNase E synthesis. PMID: 21518390
  2. The truncated RNase E750 can still bind to Hfq although the truncation significantly reduces the Hfq-binding ability. PMID: 21219461
  3. Data suggest that RraA can affect multiple components of the RNA degradosome in a dynamic, energy-dependent equilibrium. PMID: 20106955
  4. Findings suggest RraA is able to effectively modulate the catalytic activity of RNase E in vivo. PMID: 16725107
  5. expression of RraA or RraB is accompanied by specific changes in degradosome composition--and that these are in turn associated with alterations in RNA decay PMID: 16771842

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Subcellular Location
Cytoplasm.
Protein Families
RraA family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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