RRN3 Antibody

Code CSB-PA020525XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RRN3 Polyclonal antibody
Uniprot No.
Target Names
RRN3
Alternative Names
RRN3 antibody; YKL125W antibody; RNA polymerase I-specific transcription initiation factor RRN3 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RRN3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for efficient transcription initiation by RNA polymerase I. Interacts with Pol I in the absence of template DNA and stimulates recruitment of Pol I, but does not remain as part of stable preinitiation complex.
Gene References into Functions
  1. A dual role for Rrn3 in transcription initiation to stabilize a monomeric initiation competent RNA polymerase I and to drive pre-initiation complex formation. PMID: 27418187
  2. Rrn3 binding converts an inactive RNA polymerase I dimer into an initiation-competent monomeric complex.Rrn3 stabilizes monomeric RNA polymerase I. PMID: 27418309
  3. Two RNA polymerase I subunits control the binding and release of RRN3 during transcription. PMID: 18086878
Subcellular Location
Nucleus.
Protein Families
RRN3 family
Database Links

KEGG: sce:YKL125W

STRING: 4932.YKL125W

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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