Rps19 Antibody

1. Mutation of the key residue for extraribosomal function of ribosomal protein S19 cause increased grooming behaviors in mice. Results suggest an involvement of RP S19 oligomers in some anxiety-like behavior, especially grooming behavior. PMID: 27424793
2. Rps19 mutant shows behavioural phenotypes resembling that of the human Diamond-Blackfan anaemia syndrome. PMID: 27643579
3. indicate the importance of the RP S19 oligomer-induced macrophage recruitment in coagulum resorption PMID: 25329761
4. Rps19 mutant embryonic stem cells showed significant increase in p53 protein expression. PMID: 24558476
5. We report the generation of mouse models for RPS19-deficient Diamond Blackfan anemia using transgenic RNA interference that allows an inducible and graded down-regulation of Rps19. PMID: 21989989
6. generated a transgenic model expressing an RPS19 mutation in which an arginine residue is replaced with a tryptophan residue at codon 62 as a model of Diamond-Blackfan anemia PMID: 20606162
7. RPS19 mRNA and protein expression were shown to decrease during terminal erythroid differentiation. PMID: 12393682
8. Results indicate that ribosomal protein S19 (-/-) zygotes do not form blastocysts, whereas one normal Rps19 allele in mice is sufficient to maintain normal ribosomal and possibly extraribosomal functions. PMID: 15082795
9. presence of an RP S19 dimer- and C5a receptor-mediated autocrine-type augmentation mechanism during Mn II-induced apoptosis in the mouse fibroblastic cell line PMID: 15543555
10. the loss of one Rps19 allele in mice is fully compensated for at the transcriptional level with preservation of erythropoiesis PMID: 16458028
11. Study reports two mouse dark skin (Dsk) loci caused by mutations in Rps19 (ribosomal protein S19) and Rps20 (ribosomal protein S20). PMID: 18641651

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KEGG: mmu:20085

STRING: 10090.ENSMUSP00000104067

UniGene: Mm.300281