rseA Antibody

Code CSB-PA365374XA01FQR
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) rseA Polyclonal antibody
Uniprot No.
Target Names
rseA
Alternative Names
rseA; mclA; c3096; Anti-sigma-E factor RseA; Regulator of SigE; Sigma-E anti-sigma factor RseA; Sigma-E factor negative regulatory protein
Raised in
Rabbit
Species Reactivity
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Immunogen
Recombinant Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) rseA protein
Immunogen Species
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
Subcellular Location
Cell inner membrane; Single-pass type II membrane protein.
Protein Families
RseA family
Database Links

KEGG: ecc:c3096

STRING: 199310.c3096

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