rtcA Antibody

Code CSB-PA487902XA01EOP
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Product Details

Full Product Name
Rabbit anti-Escherichia coli O81 (strain ED1a) rtcA Polyclonal antibody
Uniprot No.
Target Names
rtcA
Alternative Names
rtcA antibody; ECED1_4080 antibody; RNA 3'-terminal phosphate cyclase antibody; RNA cyclase antibody; RNA-3'-phosphate cyclase antibody; EC 6.5.1.4 antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli O81 (strain ED1a)
Immunogen
Recombinant Escherichia coli O81 (strain ED1a) rtcA protein
Immunogen Species
Escherichia coli O81 (strain ED1a)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
Subcellular Location
Cytoplasm.
Protein Families
RNA 3'-terminal cyclase family, Type 1 subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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