run Antibody

Code CSB-PA326015XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) run Polyclonal antibody
Uniprot No.
Target Names
run
Alternative Names
run antibody; CG1849 antibody; Segmentation protein Runt antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) run protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plays a pivotal role in regulating the expression of other pair-rule genes such as eve, ftz, and h.
Gene References into Functions
  1. Runt-dependent regulation in the Drosophila blastoderm embryo relies on unique, target-gene-specific molecular interactions. PMID: 21325629
  2. there are two distinct steps in the repression of engrailed by Runt PMID: 12145660
  3. These proteins provide a paradigm for understanding DNA-binding-independent regulation by developmentally important transcription factors. PMID: 12732185
  4. Contrasting responses of different downstream targets to Runt in the presence or absence of Ftz is thus central to the combinatorial logic of the pair-rule to segment-polarity transition. PMID: 15102703
  5. Lilli plays an architectural role in facilitating transcriptional activation that depends both on the target gene and the developmental context PMID: 17137570

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Subcellular Location
Nucleus.
Tissue Specificity
Expressed in embryonic central and peripheral nervous system.
Database Links

KEGG: dme:Dmel_CG1849

STRING: 7227.FBpp0076971

UniGene: Dm.2688

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