Ryanodine receptor 3 Antibody

Code CSB-PA020621XA01RB
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Product Details

Uniprot No.
Alternative Names
antibody; Ryanodine receptor 3 antibody; RYR-3 antibody; RyR3 antibody; Brain ryanodine receptor-calcium release channel antibody; Brain-type ryanodine receptor antibody; Type 3 ryanodine receptor antibody
Raised in
Rabbit
Species Reactivity
Oryctolagus cuniculus (Rabbit)
Immunogen
Recombinant Oryctolagus cuniculus (Rabbit) Ryanodine receptor 3 protein
Immunogen Species
Oryctolagus cuniculus (Rabbit)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Plays a role in cellular calcium signaling. Contributes to cellular calcium ion homeostasis. Isoform 2 lacks a predicted transmembrane segment and does not form functional calcium channels by itself; however, it can form tetramers with isoforms that contain the full complement of transmembrane segments and modulate their activity.
Subcellular Location
Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Sarcoplasmic reticulum.
Protein Families
Ryanodine receptor (TC 1.A.3.1) family, RYR3 subfamily
Tissue Specificity
Detected in skeletal muscle from young rabbits and in adult diaphragm muscle (at protein level). Detected in brain, especially in corpus striatum, thalamus and hippocampus. Detected in taenia coli, uterus, vas deferens, aorta, stomach, small intestine, he
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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