sax-3 Antibody

Datasheet

Code	CSB-PA580363XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans sax-3 Polyclonal antibody

Uniprot No.

G5EBF1

Target Names

sax-3

Alternative Names

sax-3 antibody; ZK377.2Protein sax-3 antibody; Sensory axon guidance 3 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans sax-3 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Required to confine migrating sex myoblasts to the ventral muscle quadrants during their migration through the body and for multiple aspects of sensory, motor, and interneuron axon guidance.

Gene References into Functions

These data suggest that chw-1 is likely acting downstream and/or in parallel to sax-3 in axon guidance. PMID: 29653940
SAX-3 regulate convergent extension-based nerve cord assembly in C. elegans PMID: 28441532
The SAX-3 receptor stimulates axon outgrowth and the signal sequence and transmembrane domain are critical for SAX-3 membrane localization in the posterior deirid neuron of C. elegans. PMID: 23776520
SAX-3 is required in the nervous system for proper extension of ventral anterior muscle processes. PMID: 21820426
Mutants with impaired growth cone functions, such as sax-3, often exhibit abnormal terminations and inappropriate trajectories at the distal ends of the M2 axons. PMID: 12885562

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Subcellular Location

Membrane; Single-pass membrane protein.

Protein Families

Immunoglobulin superfamily, ROBO/SAX3 family

Tissue Specificity

Expressed in the AVG interneuron and the male-specific sensory neuron HOA.

Database Links

KEGG: cel:CELE_ZK377.2

STRING: 6239.ZK377.2b

UniGene: Cel.17401

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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